| Soft Tissue Fillers for Facial Rejuvenation IntroductionAging of the skin and superficial soft tissues is due to a  combination of factors, including ultraviolet radiation, genetics, gravity, facial  expression, sleep position, and/or tobacco use. Collagen, elastin, fat, and  bone diminish over time leading to loss of youthful volume of the face, structural changes of the bony foundation, and wrinkling, sagging of the skin.  Soft tissue fillers are a key component in maintaining or creating a youthful face. With the available FDA-approved products in the United States,
   Filler Selection Several injectable fillers have received  FDA-approval for cosmetic use in the United States, each with unique properties  capable of providing the results you desire.  Some fillers have properties that restore volume and achieve a lifting effect. Some fillers are designed to erase and smooth wrinkles or creases in the skin. Some fillers result in immediate volume  restoration, while other fillers restore volume over time by stimulating natural  collagen production. Some fillers are temporary, while others are permanent. Some  fillers are composed of natural substances while others are composed of  bio-compatible substances.
 Below are the most common fillers used in the  United States listed by ingredient. For specific details, please click on the  link of each product: 
								  
								    Hyaluronic acid (Juvederm Voluma, Juvederm Volbella, Juvederm Ultra & Ultra Plus, Restylane/Restylane Silk , Restylane Lyft , Belotero) 
							        Calcium hydroxyapatite (Radiesse) 
							        Autologous fat grafting
							        Polymethylmethacrylate (Artefill)
							        Human collagen (Cosmoderm, Cosmoplast)
							        Porcine collagen (Evolence)
							        Poly-lactic acid (Sculptra)
							        Microdroplet Silicon (Silikon 1000)   What  should I do before treatment?Before treatment, your provider should review your medical history,  including allergies and medicines. If you are taking blood thinners, ask your  doctor if it’s safe to discontinue prior to filler treatment. Filler treatment is contraindicated in certain situations and  should be reviewed prior to treatment.
   Do filler injections hurt?The procedures  are well tolerated. Various methods for comfort are available including gentle  nerve blocks, topical numbing cream, cooling of the skin, and/or mixing of  anesthetic solution with the filler.
   What is the recovery time?The majority of  patients have none to minimal down time. Occasionally, a bruise may develop,  which resolves in a few days. If you take a blood thinner medication, ask your  doctor if it can be discontinued prior to filler treatment. There may be some swelling noted  after the procedure, which can be minimized with ice and rarely lasts more than  a day.
  How long does it last? Filler last from a few months to several years.  Please review the information of each specific filler for more details.
 
  Are there any side  effects? Side effects are uncommon and usually minor and temporary if seen. You may  experience soreness or bruising at the injection site. Occasionally, people  experience lumpiness or irregularity in the treatment area.  These typically resolve with gentle massage  or observation. Permanent fillers can results in permanent nodules or  irregularities, so proper evaluation and technique by your provider is a  critical.
 
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